Hamideh Moravvej; Akbar Mousazadeh Halim; Maryam Yousefi; Soudabeh Givrad
Volume 15, Issue 1 , 2012, , Pages 7-10
Abstract
Background: Acne vulgaris is the most common disorder of pilosebaceous unit. Systemic antibiotics are known to be effective in its treatment. We performed this investigation to compare the efficacy of azithromycin with doxycycline in the treatment of acne vulgaris. Method: A twelve-week study was performed ...
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Background: Acne vulgaris is the most common disorder of pilosebaceous unit. Systemic antibiotics are known to be effective in its treatment. We performed this investigation to compare the efficacy of azithromycin with doxycycline in the treatment of acne vulgaris. Method: A twelve-week study was performed on 69 patients with moderate facial acne to compare the efficacy of oral azithromycin with oral doxycycline. Sixty patients completed the study. Patients in the treatment arm one were scheduled to receive 500 mg azithromycin once daily three times a week, and patients in the treatment arm two were instructed to use 100 mg doxycycline daily. All patients administered topical tretinoin cream every other night. Clinical assessment was made at baseline and then every 4 weeks. Result: There were statistically significant improvements in comedones and inflammatory lesion counts in both groups. Neither drug was shown to be more effective than the other. Conclusion: This study indicated that azithromycin had similar efficacy to doxycycline in reducing acne lesions.
Zahra Asadi-Kani; Hamideh Moravvej; Mehdi Gaisari; Sima Kavand; Marjan Saeedi
Volume 12, Suppl.3 , 2009, , Pages 27-29
Abstract
Lipomembranous panniculitis is a special type of fat necrosis which has been associated with several clinical conditions, mainly chronic venous insufficiency and connective tissue disorders such as lupus profundus, morphea, systemic sclerosis, and dermatomyositis .We report a 50 yearold woman with known ...
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Lipomembranous panniculitis is a special type of fat necrosis which has been associated with several clinical conditions, mainly chronic venous insufficiency and connective tissue disorders such as lupus profundus, morphea, systemic sclerosis, and dermatomyositis .We report a 50 yearold woman with known rheumatoid arthritis who presented with a painful indurated erythematous plaque on her right leg. Histologic examination demonstrated cystic areas of fat necrosis lined by wavy eosinophilic hyaline membrane with convoluted projections of the membrane into the cysts. This finding is diagnostic of lipomembranous panniculitis. To our knowledge, this is the first report on lipomembranous panniculitis associated with rheumatoid arthritis.
Hamideh Moravvej; Maryam Yousefi; Nahid Mohtasham; Nelda Saadat; Hamid Reza Haghighatkhah
Volume 11, Issue 3 , 2008, , Pages 108-112
Abstract
Background: Few studies have investigated on vitamin D metabolites Serum levels, and calcium homeostasis in humans receiving retinoids, despite a substantial amount of literature concerning retinoid-induced osteoporosis in animals. We prospectively measured vitamin D metabolites serum levels and calcium ...
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Background: Few studies have investigated on vitamin D metabolites Serum levels, and calcium homeostasis in humans receiving retinoids, despite a substantial amount of literature concerning retinoid-induced osteoporosis in animals. We prospectively measured vitamin D metabolites serum levels and calcium homeostasis and radiographic bone changes in short course treatment with oral isotretinoin in severe acne.Methods: 1,25-dihydroxy vitamin D and 25-hydroxy vitamin D, calcium, phosphate, Parathyroid hormone and axial spine , femoral neck radiographies were measured in 30 nodulocystic acne patients ( 17 -28 years ) before and after twenty weeks of treatment with oral isotretinoin at the recommended dose (0.75 -1 mg/kg/day) .Results: vitamin D metabolites, calcium, phosphate, Parathyroid-hormone did not change significantly and hyperostosis and other sclerotic change were not observed in any patients.Conclusion: Short course treatment with oral isotretinoin at the recommended dose did not lead to any significant changes in serum vitamin D metabolites, calcium, phosphate and Parathyroid hormone and has no effects on bone radiography in acne patients.
Hamideh Moravvej; Maryam Yousefi; Behrooz Barikbin
Volume 9, suppl.1 , 2006, , Pages 6-6
Abstract
Lupoid leishmaniasis is an unusual complication of acute cutaneous leishmaniasis which can represent a diagnostic and therapeutic challenge. The disease is actually a reactivation of an earlier acute cutaneous infection. It usually starts close to or in the scar of previous lesion and can cause severe ...
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Lupoid leishmaniasis is an unusual complication of acute cutaneous leishmaniasis which can represent a diagnostic and therapeutic challenge. The disease is actually a reactivation of an earlier acute cutaneous infection. It usually starts close to or in the scar of previous lesion and can cause severe destruction. Its diagnosis is complicated by the sparsity of the microorganisms in the direct smear and the tissue. The present report deals with a middle age Iranian woman presented to us with multiple scars on the whole face and also multiple red-down papules and nodules around these scars. After three years of clinical, histopathological and laboratory investigations and treating with no or minimal success for the diagnosed of discoid lupus erythematosus, sarcoidosis and lupus vulgaris, finally was diagnosed and treated successfully as lupoid leishmaniasis with meglumine antimoniate (Glucantime).